Recombinant Human HOXC11, His-tagged

• Cat.No.: HOXC11-15916H
• Product Overview: Recombinant human HOXC11 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: HOXC11 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
• Molecular Mass: 36.1kDa (327aa)
• Protein length: 1-304aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMFNSVNL GNFCSPSRKE RGADFGERGS CASNLYLPSC TYYMPEFSTV SSFLPQAPSR QISYPYSAQV PPVREVSYGL EPSGKWHHRN SYSSCYAAAD ELMHRECLPP STVTEILMKN EGSYGGHHHP SAPHATPAGF YSSVNKNSVL PQAFDRFFDN AYCGGGDPPA EPPCSGKGEA KGEPEAPPAS GLASRAEAGA EAEAEEENTN PSSSGSAHSV AKEPAKGAAP NAPRTRKKRC PYSKFQIREL EREFFFNVYI NKEKRLQLSR MLNLTDRQVK IWFQNRRMKE KKLSRDRLQY FSGNPLL
• Purity: >80% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: HOXC11 homeobox C11 [ Homo sapiens ]
• Official Symbol: HOXC11
• Synonyms: HOXC11; homeobox C11; homeo box C11 , HOX3H; homeobox protein Hox-C11; homeo box C11; homeobox protein Hox-3H; HOX3H; MGC4906
• Gene ID: 3227
• mRNA Refseq: NM_014212
• Protein Refseq: NP_055027
• MIM: 605559
• UniProt ID: O43248
• Chromosome Location: 12q13.13
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity