Recombinant Human CAV1, His-tagged

• Cat.No.: CAV1-10749H
• Product Overview: Recombinant Human CAV1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 11-179a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CAV1 caveolin 1, caveolae protein, 22kDa [ Homo sapiens ]
• Official Symbol: CAV1
• Synonyms: CAV1; caveolin 1, caveolae protein, 22kDa; CAV, caveolin 1, caveolae protein, 22kD; caveolin-1; cell growth-inhibiting protein 32; CGL3; BSCL3; VIP21; MSTP085
• Gene ID: 857
• mRNA Refseq: NM_001172895
• Protein Refseq: NP_001166366
• MIM: 601047
• UniProt ID: Q03135
• Chromosome Location: 7q31
• Pathway: ALK1 signaling events, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Basigin interactions, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem
• Function: cholesterol binding; kinase binding; nitric-oxide synthase binding; patched binding; peptidase activator activity; protein binding; protein complex scaffold; receptor binding; structural molecule activity; syntaxin binding