Recombinant Human CCIN, GST-tagged

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Recombinant Human CCIN, GST-tagged

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Cat.No. : CCIN-10829H
Product Overview : Recombinant Human CCIN protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5 UTR, have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : N-term-351a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CCIN calicin [ Homo sapiens ]
Official Symbol : CCIN
Synonyms : CCIN; calicin
Gene ID : 881
mRNA Refseq : NM_005893.2
Protein Refseq : NP_005884.2
MIM : 603960
UniProt ID : Q13939
Chromosome Location : 9p13.3
Function : structural constituent of cytoskeleton
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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