Recombinant Human DEFB1, GST-tagged
Cat.No. : | DEFB1-11929H |
Product Overview : | Recombinant Human DEFB1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Specification
- Gene Information
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Description : | Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-68a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | DEFB1 defensin, beta 1 [ Homo sapiens ] |
Official Symbol : | DEFB1 |
Synonyms : | DEFB1; defensin, beta 1; beta-defensin 1; BD1; DEFB 1; DEFB101; HBD 1; HBD1; MGC51822; BD-1; beta-defensin-1; DEFB-1; |
Gene ID : | 1672 |
mRNA Refseq : | NM_005218 |
Protein Refseq : | NP_005209 |
MIM : | 602056 |
UniProt ID : | P60022 |
Chromosome Location : | 8p23.1 |
Pathway : | Beta defensins, organism-specific biosystem; Defensins, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, the antimicrobial properties of DEFB1 make it a potential target for the development of novel therapeutics against various infectious diseases.
Research suggests that combining DEFB1 with conventional antibiotics may enhance the overall antimicrobial activity and reduce the risk of antibiotic resistance.
DEFB1 plays a role in maintaining the balance of the microbiome by preventing the overgrowth of harmful microorganisms. It contributes to the dynamic equilibrium in the microbial community.
Some studies suggest that DEFB1 may have a role in cancer, with evidence indicating both tumor-promoting and tumor-suppressing effects depending on the specific context.
Yes, variations in the DEFB1 gene can influence its expression levels, impacting an individual's susceptibility to certain infections and inflammatory conditions.
Customer Reviews (3)
Write a reviewthe stability of the DEFB1 protein enables me to conduct experiments over an extended period, reducing the need for frequent restocking and promoting experimental consistency.
The DEFB1 protein offers significant advantages in trials due to its high quality, purity, and stability.
the manufacturer's exceptional support greatly enhances my research process.
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