"EIF2AK1" Related Products

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Recombinant Human EIF2AK1, GST-tagged

Cat.No.: EIF2AK1-12349H
Product Overview: Recombinant Human EIF2AK1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: C-term-350a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 [ Homo sapiens ]
Official Symbol: EIF2AK1
Synonyms: EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1; heme regulated initiation factor 2 alpha kinase; HRI; KIAA1369; heme-regulated inhibitor; heme-regulated repressor; heme-controlled repressor; heme sensitive initiation factor 2a kinase; heme-regulated initiation factor 2-alpha kinase; hemin-sensitive initiation factor 2-alpha kinase; heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; HCR;
Gene ID: 27102
mRNA Refseq: NM_001134335
Protein Refseq: NP_001127807
MIM: 613635
UniProt ID: Q9BQI3
Chromosome Location: 7p22
Pathway: Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Measles, organism-specific biosystem;
Function: ATP binding; eukaryotic translation initiation factor 2alpha kinase activity; heme binding; nucleotide binding; protein homodimerization activity;

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