Recombinant Human EIF2AK1, GST-tagged


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Recombinant Human EIF2AK1, GST-tagged

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Cat.No. : EIF2AK1-12349H
Product Overview : Recombinant Human EIF2AK1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-350a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 [ Homo sapiens ]
Official Symbol : EIF2AK1
Synonyms : EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1; heme regulated initiation factor 2 alpha kinase; HRI; KIAA1369; heme-regulated inhibitor; heme-regulated repressor; heme-controlled repressor; heme sensitive initiation factor 2a kinase; heme-regulated initiation factor 2-alpha kinase; hemin-sensitive initiation factor 2-alpha kinase; heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; HCR;
Gene ID : 27102
mRNA Refseq : NM_001134335
Protein Refseq : NP_001127807
MIM : 613635
UniProt ID : Q9BQI3
Chromosome Location : 7p22
Pathway : Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Measles, organism-specific biosystem;
Function : ATP binding; eukaryotic translation initiation factor 2alpha kinase activity; heme binding; nucleotide binding; protein homodimerization activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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