Recombinant Human GAPDHS, His-tagged

• Cat.No.: GAPDHS-13154H
• Product Overview: Recombinant Human GAPDHS protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: C-term-351a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [ Homo sapiens ]
• Official Symbol: GAPDHS
• Synonyms: GAPDHS; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; GAPDS; glyceraldehyde-3-phosphate dehydrogenase, testis-specific; GAPD2; GAPDH 2; spermatogenic glyceraldehyde-3-phosphate dehydrogenase; spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; HSD-35; GAPDH-2
• Gene ID: 26330
• mRNA Refseq: NM_014364
• Protein Refseq: NP_055179
• MIM: 609169
• UniProt ID: O14556
• Chromosome Location: 19q13.1
• Pathway: Gluconeogenesis, organism-specific biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem; Glycolysis and Gluconeogenesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem
• Function: NAD binding; NADP binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; oxidoreductase activity; protein binding