Recombinant Human GFI1, His-tagged GFI1-13229H

Recombinant Human GFI1, His-tagged


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Recombinant Human GFI1, His-tagged

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Cat.No. : GFI1-13229H
Product Overview : Recombinant Human GFI1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-422a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : GFI1 growth factor independent 1 transcription repressor [ Homo sapiens ]
Official Symbol : GFI1
Synonyms : GFI1; growth factor independent 1 transcription repressor; growth factor independent 1 , ZNF163; zinc finger protein Gfi-1; zinc finger protein 163; growth factor independence-1; growth factor independent protein 1; SCN2; GFI-1; ZNF163; FLJ94509;
Gene ID : 2672
mRNA Refseq : NM_001127215
Protein Refseq : NP_001120687
MIM : 600871
UniProt ID : Q99684
Chromosome Location : 1p22
Pathway : Validated targets of C-MYC transcriptional repression, organism-specific biosystem;
Function : DNA binding; metal ion binding; protein binding; transcription regulatory region DNA binding; zinc ion binding;

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