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Recombinant Human GMDS, His-tagged

Cat.No. : GMDS-13330H
Product Overview : Recombinant Human GMDS protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Source : E.coli
Species : Human
Tag : His
Protein length : 1-372a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : GMDS GDP-mannose 4,6-dehydratase [ Homo sapiens ]
Official Symbol : GMDS
Synonyms : GMDS; GDP-mannose 4,6-dehydratase; GDP-mannose 4,6 dehydratase; GMD; SDR3E1; short chain dehydrogenase/reductase family 3E; member 1; GDP-D-mannose dehydratase; short chain dehydrogenase/reductase family 3E, member 1;
Gene ID : 2762
mRNA Refseq : NM_001253846
Protein Refseq : NP_001240775
MIM : 602884
UniProt ID : O60547
Chromosome Location : 6p25
Pathway : Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; GDP-L-fucose biosynthesis I (from GDP-D-mannose), organism-specific biosystem; Metabolic pathways, organism-specific biosystem; colanic acid building blocks biosynthesis, organism-specific biosystem;
Function : GDP-mannose 4,6-dehydratase activity; GDP-mannose 4,6-dehydratase activity; NADP+ binding; coenzyme binding; lyase activity; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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