"GMDS" Related Products


Recombinant Human GMDS, His-tagged

Cat.No.: GMDS-13330H
Product Overview: Recombinant Human GMDS protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Source: E.coli
Species: Human
Tag: His
Protein length: 1-372a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: GMDS GDP-mannose 4,6-dehydratase [ Homo sapiens ]
Official Symbol: GMDS
Synonyms: GMDS; GDP-mannose 4,6-dehydratase; GDP-mannose 4,6 dehydratase; GMD; SDR3E1; short chain dehydrogenase/reductase family 3E; member 1; GDP-D-mannose dehydratase; short chain dehydrogenase/reductase family 3E, member 1;
Gene ID: 2762
mRNA Refseq: NM_001253846
Protein Refseq: NP_001240775
MIM: 602884
UniProt ID: O60547
Chromosome Location: 6p25
Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; GDP-L-fucose biosynthesis I (from GDP-D-mannose), organism-specific biosystem; Metabolic pathways, organism-specific biosystem; colanic acid building blocks biosynthesis, organism-specific biosystem;
Function: GDP-mannose 4,6-dehydratase activity; GDP-mannose 4,6-dehydratase activity; NADP+ binding; coenzyme binding; lyase activity; nucleotide binding;

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