Recombinant Human HERC6, His-tagged
Cat.No. : | HERC6-13741H |
Product Overview : | Recombinant Human HERC6 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]). |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 11-98a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [ Homo sapiens ] |
Official Symbol : | HERC6 |
Synonyms : | HERC6; HECT and RLD domain containing E3 ubiquitin protein ligase family member 6; hect domain and RLD 6; probable E3 ubiquitin-protein ligase HERC6; FLJ20637; potential ubiquitin ligase; HECT domain and RCC1-like domain-containing protein 6; |
Gene ID : | 55008 |
mRNA Refseq : | NM_001165136 |
Protein Refseq : | NP_001158608 |
MIM : | 609249 |
UniProt ID : | Q8IVU3 |
Chromosome Location : | 4q22 |
Function : | acid-amino acid ligase activity; ligase activity; ubiquitin-protein ligase activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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