Recombinant Human HERC6, His-tagged HERC6-13741H

Recombinant Human HERC6, His-tagged


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Recombinant Human HERC6, His-tagged

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Cat.No. : HERC6-13741H
Product Overview : Recombinant Human HERC6 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Source : E.coli
Species : Human
Tag : His
Protein length : 11-98a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [ Homo sapiens ]
Official Symbol : HERC6
Synonyms : HERC6; HECT and RLD domain containing E3 ubiquitin protein ligase family member 6; hect domain and RLD 6; probable E3 ubiquitin-protein ligase HERC6; FLJ20637; potential ubiquitin ligase; HECT domain and RCC1-like domain-containing protein 6;
Gene ID : 55008
mRNA Refseq : NM_001165136
Protein Refseq : NP_001158608
MIM : 609249
UniProt ID : Q8IVU3
Chromosome Location : 4q22
Function : acid-amino acid ligase activity; ligase activity; ubiquitin-protein ligase activity;

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