Recombinant Human DNAJC15, His-tagged

• Cat.No.: DNAJC15-2300H
• Product Overview: Recombinant human DNAJC15 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: DNAJC15 contains 1 J domain. This protein is expressed ubiquitously and located on the membrane. DNAJC15 is absent or down-regulated in many advanced cases of ovarian adenocarcinoma, due to hypermethylation and allelic loss. Loss of expression correlates with increased resistance to antineoplastic drugs, such as cisplatin.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT.
• Molecular Mass: 12.8 kDa
• Protein length: 116aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSFRIWKPL EQVITETAKK ISTPSFSSYY KGGFEQKMSR REAGLILGVS PSAGKAKIRT AHRRVMILNHPDKGGSPYVA AKINEAKDLL ETTTKH
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml

Gene Information

• Gene Name: DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 [ Homo sapiens ]
• Official Symbol: DNAJC15
• Synonyms: DNAJC15; DnaJ (Hsp40) homolog, subfamily C, member 15; DnaJ (Hsp40) homolog, subfamily D, member 1 , DNAJD1; dnaJ homolog subfamily C member 15; MCJ; DNAJ domain-containing; methylation-controlled J protein; cell growth-inhibiting gene 22 protein; DnaJ (Hsp40) homolog, subfamily D, member 1; HSD18; DNAJD1
• Gene ID: 29103
• mRNA Refseq: NM_013238
• Protein Refseq: NP_037370
• UniProt ID: Q9Y5T4
• Chromosome Location: 13q14.1
• Function: heat shock protein binding