"BRDT" Related Products

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Recombinant Human BRDT, His-tagged

Cat.No.: BRDT-1912H
Product Overview: Recombinant protein includes Bromo 1 domain (257-382 aa) with N-terminal His-tag.
Description: BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin.
Source: E. coli
Species: Human
Tag: His
Appearance: Liquid
Form: rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
Molecular Mass: 14.9 kDa (126 aa, 257-382 aa + NT His Tag)
Protein length: 257-382 aa
Purity: ≥98% by SDS-PAGE
Usage: For Research Use Only! Not For Use in Humans.
Storage: Stable for 1 year at –80°C. Avoid multiple freeze/thaw cycles as activity may decrease.
Gene Name: BRDT bromodomain, testis-specific [ Homo sapiens (human) ]
Official Symbol: BRDT
Synonyms: BRDT; bromodomain, testis-specific; CT9; BRD6; bromodomain testis-specific protein; RING3-like protein; cancer/testis antigen 9
Gene ID: 676
mRNA Refseq: NM_001726
Protein Refseq: NP_001717
MIM: 602144
UniProt ID: Q58F21
Chromosome Location: 1p22.1
Function: histone acetyl-lysine binding; histone binding; transcription coactivator activity

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