Recombinant Human BRDT, His-tagged

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Recombinant Human BRDT, His-tagged

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Cat.No. : BRDT-1912H
Product Overview : Recombinant protein includes Bromo 1 domain (257-382 aa) with N-terminal His-tag.
Description : BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin.
Source : E. coli
Species : Human
Tag : His
Appearance : Liquid
Form : rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
Molecular Mass : 14.9 kDa (126 aa, 257-382 aa + NT His Tag)
Protein length : 257-382 aa
Purity : ≥98% by SDS-PAGE
Usage : For Research Use Only! Not For Use in Humans.
Storage : Stable for 1 year at –80°C. Avoid multiple freeze/thaw cycles as activity may decrease.
Gene Name : BRDT bromodomain, testis-specific [ Homo sapiens (human) ]
Official Symbol : BRDT
Synonyms : BRDT; bromodomain, testis-specific; CT9; BRD6; bromodomain testis-specific protein; RING3-like protein; cancer/testis antigen 9
Gene ID : 676
mRNA Refseq : NM_001726
Protein Refseq : NP_001717
MIM : 602144
UniProt ID : Q58F21
Chromosome Location : 1p22.1
Function : histone acetyl-lysine binding; histone binding; transcription coactivator activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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