|Product Overview:||Recombinant Human CD58(Met1-Arg215) fused with His tag at C-terminal was expressed in HEK293.|
|Description:||CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.|
|Predicted N Terminal:||Phe 29|
|Form:||Lyophilized from sterile PBS, pH 7.4|
|Molecular Mass:||The recombinant human CD58 consists of 198 amino acids and predicts a molecular mass of 22.9 KDa. It migrates as an approximately 38-43 Kda band in SDS-PAGE under reducing conditions.|
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Purity:||> 95 % as determined by SDS-PAGE|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70 centigrade.|
|Storage:||Store it under sterile conditions at -20 centigrade to -80 centigrade upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.
|Gene Name:||CD58 CD58 molecule [ Homo sapiens ]|
|Synonyms:||CD58; CD58 molecule; CD58 antigen, (lymphocyte function associated antigen 3) , LFA3; lymphocyte function-associated antigen 3; surface glycoprotein LFA-3; CD58 antigen, (lymphocyte function-associated antigen 3); ag3; LFA3; LFA-3; FLJ23181; FLJ43722;|
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