Recombinant Human AKAP5, His-tagged
Cat.No. : | AKAP5-23H |
Product Overview : | Recombinant Human A-Kinase Anchor Protein 5/AKAP5 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Gln427) of Human AKAP5 fused with a 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | A-Kinase Anchor Protein 5 (AKAP5) is a member of the AKAP family. AKAP5 contains one AKAP domain and is predominantly expressed in the cerebral cortex. AKAP5 may anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. AKAP5 association with to the β-2-adrenergic receptor (β2-AR) not only regulates β2-AR signaling pathway, but also the activation by PKA by switching off the β2-AR signaling cascade. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
AA Sequence : | METTISEIHVENKDEKRSAEGSPGA ERQKEKASMLCFKRRKKAAKALKPK AGSEAADVARKCPQE AGASDQPEPTRGAWASLKRLVTRRK RSESSKQQKPLEGEMQPAINAEDAD LSKKKAKSRLKIPCI KFPRGPKRSNHSKIIEDSDCSIKVQ EEAEILDIQTQTPLNDQATKAKSTQ DLSEGISRKDGDEVC ESNVSNSITSGEKVISVELGLDNGH SAIQTGTLILEEIETIKEKQDVQPQ QASPLETSETDHQQP VLSDVPPLPAIPDQQIVEEASNSTL ESAPNGKDYESTEIVAEETKPKDTE LSQESDFKENGITEE KSKSEESKRMEPIAIIITDTEISEF DVTKSKNVPKQFLISAENEQVGVFA NDNGFEDRTSEQYET LLIETASSLVKNAIQLSIEQLVNEM ASDDNKINNLLQVDHHHHHH |
Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Gene Name : | AKAP5 A kinase (PRKA) anchor protein 5 [ Homo sapiens ] |
Official Symbol : | AKAP5 |
Synonyms : | AKAP5; A kinase (PRKA) anchor protein 5; A-kinase anchor protein 5; AKAP75; AKAP79; AKAP-5; AKAP 79; A-kinase anchor protein 79 kDa; A-kinase anchor protein, 79kDa; A-kinase anchoring protein 75/79; cAMP-dependent protein kinase regulatory subunit II high affinity binding protein; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein; H21; |
Gene ID : | 9495 |
mRNA Refseq : | NM_004857 |
Protein Refseq : | NP_004848 |
MIM : | 604688 |
UniProt ID : | P24588 |
Chromosome Location : | 14q21-q24 |
Pathway : | Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Receptor Binding And Downstream Transmission In ThePostsynaptic Cell, organism-specific biosystem; |
Function : | adenylate cyclase binding; calmodulin binding; protein binding; protein kinase A binding; |
Products Types
◆ Recombinant Protein | ||
AKAP5-2451H | Recombinant Human AKAP5 Protein, His (Fc)-Avi-tagged | +Inquiry |
AKAP5-431M | Recombinant Mouse AKAP5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Akap5-110M | Recombinant Mouse Akap5 Protein, His&GST-tagged | +Inquiry |
AKAP5-714H | Recombinant Human AKAP5 | +Inquiry |
Akap5-3029R | Recombinant Rat Akap5, His-tagged | +Inquiry |
◆ Lysates | ||
AKAP5-8939HCL | Recombinant Human AKAP5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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