Recombinant Human CCNY, GST-tagged

• Cat.No.: CCNY-130H
• Product Overview: Recombinant human Cyclin Y (2-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: Cyclin Y belongs to the highly conserved cyclin family. The members of the cyclin family are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclin Y plays an important role in the processes of transcription, DNA repair, and cell cycle progression. Cyclin Y regulates cyclin-dependent kinases. Cyclin Y is an isoform of CCNY that is also known as CFP1 variant A which has a calculated molecular mass of 36.9 kD. Cyclin Y specifically activates transcription through the MYC promoter.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~65 kDa
• Purity: >80% by densitometry
• Applications: Western Blot
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μl

Gene Information

• Gene Name: CCNY cyclin Y [ Homo sapiens ]
• Official Symbol: CCNY
• Synonyms: CCNY; cyclin Y; C10orf9, chromosome 10 open reading frame 9; cyclin-Y; CBCP1; CFP1; cyc-Y; cyclin-X; cyclin box protein 1; cyclin fold protein 1; cyclin-box carrying protein 1; CCNX; C10orf9; FLJ95513
• Gene ID: 219771
• mRNA Refseq: NM_145012
• Protein Refseq: NP_659449
• MIM: 612786
• UniProt ID: Q8ND76
• Chromosome Location: 10p11.22
• Function: cyclin-dependent protein kinase regulator activity; protein binding; protein kinase binding