"CDKL3" Related Products


Recombinant Human CDKL3, GST-tagged

Cat.No.: CDKL3-148H
Product Overview: Recombinant full-length human CDKL3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: CDKL3 or cyclin-dependent kinase-like 3 is a member of cyclin-dependent protein kinase (CDK) family which is highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and is known to be important regulators of cell cycle progression and cellular proliferation. CDKL3 is a novel CDC2-related kinase with features of both mitogen-activated protein kinases and cyclin-dependent kinases. CDKL3 is identified as a gene absent in leukemic patients with chromosome 5q deletion and this loss may be an important determinant of dysmyelopoiesis.
Source: Sf9 insect cells using baculovirus
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass: ~98 kDa
Purity: >70% by densitometry
Applications: Western Blot
Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.1 μg/μl
Gene Name: CDKL3 cyclin-dependent kinase-like 3 [ Homo sapiens ]
Official Symbol: CDKL3
Synonyms: CDKL3; cyclin-dependent kinase-like 3; NKIAMRE; serine threonine protein kinase NKIAMRE; serine-threonine protein kinase NKIAMRE; serine/threonine-protein kinase NKIAMRE;
Gene ID: 51265
mRNA Refseq: NM_001113575
Protein Refseq: NP_001107047
MIM: 608459
UniProt ID: Q8IVW4
Chromosome Location: 5q31
Function: ATP binding; cyclin-dependent protein kinase activity; nucleotide binding; protein kinase activity;

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