Native Swine Haptoglobin


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Native Swine Haptoglobin

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Cat.No. : HP-193S
Product Overview : Purified Native Porcine Serum Haptoglobin.
Description : Haptoglobin (frequently abbreviated as Hp) is a protein in the blood plasma that binds free hemoglobin released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system (mostly the spleen). Haptoglobin is a serum protein that consists of two alpha and two beta chains connected by disulfide bridges. It acts as a hemoglobin scavenger and has been associated with protease inhibitory activity. It is a positive acute phase reactant, the levels of which increase significantly in pig in response to inflammation, tissue injury or disease.
Source : Porcine Serum
Species : Porcine
Form : Liquid in 10mM Sodium Phosphate pH 7.2, 150Mm NaCl
Purity : >90% by SDS-PAGE
Storage : Store at< -20>
Concentration : Typically >0.5 mg/mL
Gene Name : HP haptoglobin [ Sus scrofa ]
Official Symbol : HP
Synonyms : haptoglobin; zonulin; haptoglobin alpha 1S
Gene ID : 397061
mRNA Refseq : NM_214000
Protein Refseq : NP_999165
UniProt ID : Q8SPS7
Chromosome Location : 6p15-p14; 6
Pathway : Binding and Uptake of Ligands by Scavenger Receptors, organism-specific biosystem; Scavenging of heme from plasma, organism-specific biosystem
Function : antioxidant activity; catalytic activity; hemoglobin binding

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