Native Swine Haptoglobin

Cat.No.: HP-193S
Product Overview: Purified Native Porcine Serum Haptoglobin.
Description: Haptoglobin (frequently abbreviated as Hp) is a protein in the blood plasma that binds free hemoglobin released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system (mostly the spleen). Haptoglobin is a serum protein that consists of two alpha and two beta chains connected by disulfide bridges. It acts as a hemoglobin scavenger and has been associated with protease inhibitory activity. It is a positive acute phase reactant, the levels of which increase significantly in pig in response to inflammation, tissue injury or disease.
Source: Porcine Serum
Species: Porcine
Form: Liquid in 10mM Sodium Phosphate pH 7.2, 150Mm NaCl
Purity: >90% by SDS-PAGE
Storage: Store at< -20>
Concentration: Typically >0.5 mg/mL
Gene Name: HP haptoglobin [ Sus scrofa ]
Official Symbol: HP
Synonyms: haptoglobin; zonulin; haptoglobin alpha 1S
Gene ID: 397061
mRNA Refseq: NM_214000
Protein Refseq: NP_999165
UniProt ID: Q8SPS7
Chromosome Location: 6p15-p14; 6
Pathway: Binding and Uptake of Ligands by Scavenger Receptors, organism-specific biosystem; Scavenging of heme from plasma, organism-specific biosystem
Function: antioxidant activity; catalytic activity; hemoglobin binding

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