Native Swine Haptoglobin

• Cat.No.: HP-193S
• Product Overview: Purified Native Porcine Serum Haptoglobin.

Specification

• Description: Haptoglobin (frequently abbreviated as Hp) is a protein in the blood plasma that binds free hemoglobin released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system (mostly the spleen). Haptoglobin is a serum protein that consists of two alpha and two beta chains connected by disulfide bridges. It acts as a hemoglobin scavenger and has been associated with protease inhibitory activity. It is a positive acute phase reactant, the levels of which increase significantly in pig in response to inflammation, tissue injury or disease.
• Source: Porcine Serum
• Species: Porcine
• Form: Liquid in 10mM Sodium Phosphate pH 7.2, 150Mm NaCl
• Purity: >90% by SDS-PAGE
• Storage: Store at< -20>
• Concentration: Typically >0.5 mg/mL

Gene Information

• Gene Name: HP haptoglobin [ Sus scrofa ]
• Official Symbol: HP
• Synonyms: haptoglobin; zonulin; haptoglobin alpha 1S
• Gene ID: 397061
• mRNA Refseq: NM_214000
• Protein Refseq: NP_999165
• UniProt ID: Q8SPS7
• Chromosome Location: 6p15-p14; 6
• Pathway: Binding and Uptake of Ligands by Scavenger Receptors, organism-specific biosystem; Scavenging of heme from plasma, organism-specific biosystem
• Function: antioxidant activity; catalytic activity; hemoglobin binding