Active Recombinant Human ACACA protein, FLAG/His-tagged
Cat.No. : | ACACA-1850H |
Product Overview : | Recombinant Human ACACA(1–2383 aa) fused with FLAG and His tag at C-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Source : | Insect cells |
Species : | Human |
Tag : | FLAG/His |
Form : | 50 mM Tris-HCl, pH 8.0, 500 mM NaCl, 10% glycerol, 1 mM DTT, 100 µg/ml FLAG peptide |
Bio-activity : | 42.5 pmol/min/µg. |
Molecular Mass : | 271 kDa |
Purity : | >70% |
Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Storage : | >6 months at –80 centigrade |
Concentration : | 0.25 mg/ml |
Gene Name : | ACACA acetyl-CoA carboxylase alpha [ Homo sapiens ] |
Official Symbol : | ACACA |
Synonyms : | ACACA; acetyl-CoA carboxylase alpha; ACAC, ACC, acetyl Coenzyme A carboxylase alpha; acetyl-CoA carboxylase 1; ACC1; acetyl CoA carboxylase 1; ACC-alpha; acetyl-Coenzyme A carboxylase alpha; ACC; ACAC; ACCA; ACACAD; |
Gene ID : | 31 |
mRNA Refseq : | NM_198834 |
Protein Refseq : | NP_942131 |
MIM : | 200350 |
UniProt ID : | Q13085 |
Chromosome Location : | 17q21 |
Pathway : | AMPK signaling, organism-specific biosystem; ChREBP activates metabolic gene expression, organism-specific biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Fatty Acyl-CoA Biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; |
Function : | ATP binding; acetyl-CoA carboxylase activity; biotin binding; biotin carboxylase activity; ligase activity; metal ion binding; nucleotide binding; protein binding; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAcetyl-CoA carboxylase alpha protein performs its function through the transfer of a carboxyl group from bicarbonate to acetyl-CoA.
Acetyl-CoA carboxylase alpha protein plays important roles in energy metabolism, fatty acid synthesis, and insulin signaling.
The expression of acetyl-CoA carboxylase alpha protein is regulated by transcriptional and post-transcriptional mechanisms.
Acetyl-CoA carboxylase alpha protein is closely involved in the regulation of lipid metabolism.
Acetyl-CoA carboxylase alpha protein interacts with various cellular components, including cytoskeletal proteins and membrane lipids.
Acetyl-CoA carboxylase alpha protein is implicated in various human diseases, such as obesity, diabetes, and cancer.
The primary function of acetyl-CoA carboxylase alpha protein is to catalyze the conversion of acetyl-CoA to malonyl-CoA.
Modulating the activity of acetyl-CoA carboxylase alpha protein is a potential therapeutic strategy for metabolic disorders and cancer.
Acetyl-CoA carboxylase alpha protein is a multi-subunit enzyme with a biotin carboxylase domain and a carboxyltransferase domain.
The regulation of acetyl-CoA carboxylase alpha protein involves multiple cellular pathways, including AMPK and mTOR signaling.
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