Active Recombinant Human DLL1, Fc-tagged
Cat.No. : | DLL1-218H |
Product Overview : | Signal peptide and extracellular domain of human DLL1 (aa 1-545) are fused at the C-terminus to the Fc portion of human IgG1. |
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Description : | DLL1 (Delta-like protein; Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor. |
Source : | CHO Cells |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized. Contains PBS. |
Bio-activity : | Inhibits adipogenesis of 3T3L-1 cells. Induces Hes-1 in 3T3L-1 cells. |
Molecular Mass : | ~100kDa (SDS-PAGE) |
Purity : | ≥90% (SDS-PAGE) |
Stability : | Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
Publication : |
Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self‐Renewal Pathway. (2016)
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Gene Name : | DLL1 delta-like 1 (Drosophila) [ Homo sapiens ] |
Official Symbol : | DLL1 |
Synonyms : | DLL1; delta-like 1 (Drosophila); delta (Drosophila) like 1; delta-like protein 1; H-Delta-1; drosophila Delta homolog 1; DL1; Delta; DELTA1; |
Gene ID : | 28514 |
mRNA Refseq : | NM_005618 |
Protein Refseq : | NP_005609 |
MIM : | 606582 |
UniProt ID : | O00548 |
Chromosome Location : | 6q13-q22.33 |
Pathway : | Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem; Presenilin action in Notch and Wnt signaling, organism-specific biosystem; Signal Transduction, organism-specific biosystem; |
Function : | Notch binding; calcium ion binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
Dll1-4079R | Active Recombinant Rat Dll1 protein(Met1-Ser534), His-tagged | +Inquiry |
Dll1-2580M | Recombinant Mouse Dll1 Protein, Myc/DDK-tagged | +Inquiry |
DLL1-2802H | Recombinant Human DLL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DLL1-200H | Recombinant Human DLL1 Protein, His-tagged | +Inquiry |
DLL1-1546R | Recombinant Rat DLL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DLL1-001RCL | Recombinant Rat DLL1 cell lysate | +Inquiry |
DLL1-2461HCL | Recombinant Human DLL1 cell lysate | +Inquiry |
DLL1-2029MCL | Recombinant Mouse DLL1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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