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Recombinant Human MED1, GST-tagged

Cat.No. : MED1-800H
Product Overview : Recombinant Human MED1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Source : E.coli
Species : Human
Tag : GST
Protein length : 207-556aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : MED1 mediator complex subunit 1 [ Homo sapiens ]
Official Symbol : MED1
Synonyms : MED1; mediator complex subunit 1; PPAR binding protein , PPARBP, PPARGBP, TRIP2; mediator of RNA polymerase II transcription subunit 1; CRSP1; CRSP200; DRIP230; PBP; RB18A; TRAP220; ARC205; TRIP-2; PPAR binding protein; PPAR-binding protein; PPARG binding protein; TR-interacting protein 2; p53 regulatory protein RB18A; thyroid receptor interacting protein 2; thyroid receptor-interacting protein 2; vitamin D receptor-interacting protein 230 kD; activator-recruited cofactor 205 kDa component; peroxisome proliferator-activated receptor-binding protein; vitamin D receptor-interacting protein complex component DRIP205; thyroid hormone receptor-associated protein complex 220 kDa component; thyroid hormone receptor-associated protein complex component TRAP220; TRIP2; PPARBP; DRIP205; PPARGBP; MGC71488;
Gene ID : 5469
mRNA Refseq : NM_004774
Protein Refseq : NP_004765
MIM : 604311
UniProt ID : Q15648
Chromosome Location : 17q12
Pathway : BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Energy Metabolism, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem;
Function : DNA binding; LBD domain binding; RNA polymerase II transcription cofactor activity; chromatin binding; core promoter binding; estrogen receptor binding; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor binding; ligand-dependent

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there specific cancer types where MED1 protein is particularly relevant in clinical diagnostics? 11/24/2021

MED1's significance varies among cancer types; it has been studied extensively in breast cancer, where its expression levels can correlate with prognosis.

What clinical implications does the overexpression of MED1 have in cancer treatment? 06/16/2021

Elevated MED1 levels may influence the response to certain cancer therapies, making it a potential biomarker for treatment outcomes.

How does understanding MED1 protein function contribute to personalized medicine approaches in cancer treatment? 09/02/2020

Tailoring cancer treatments based on the molecular characteristics of MED1 and its interactions can enhance the efficacy of personalized medicine strategies.

How is the expression of MED1 protein linked to cancer development? 08/06/2017

Aberrant expression of MED1 has been associated with various cancers, where it can either promote or suppress tumor growth depending on the context.

In what ways does MED1 protein interact with hormone receptors, and what implications does this have for endocrine-related diseases? 11/19/2016

MED1 interacts with hormone receptors, impacting hormonal signaling pathways, and dysregulation of these interactions is implicated in endocrine-related diseases, including hormonal cancers.

Customer Reviews (3)

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01/04/2023

    Their commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.

    04/26/2019

      The MED1 protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.

      06/17/2017

        This flexibility enables researchers like myself to tailor MED1 protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.

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