Recombinant Human MUSK, GST-tagged
Cat.No. : | MUSK-105H |
Product Overview : | Human MUSK partial ORF ( NP_005583, 301 a.a. - 400 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.63 kDa |
AA Sequence : | ISIAEWSKPQKDNKGYCAQYRGEVC NAVLAKDALVFLNTSYADPEEAQEL LVHTAWNELKVVSPVCRPAAEALLC NHIFQECSPGVVPTPIPICREYCLA |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MUSK muscle, skeletal, receptor tyrosine kinase [ Homo sapiens (human) ] |
Official Symbol : | MUSK |
Synonyms : | MUSK; muscle, skeletal, receptor tyrosine kinase; muscle, skeletal receptor tyrosine-protein kinase; muscle-specific kinase receptor; muscle-specific tyrosine-protein kinase receptor; EC 2.7.10.1 |
Gene ID : | 4593 |
mRNA Refseq : | NM_005592 |
Protein Refseq : | NP_005583 |
MIM : | 601296 |
UniProt ID : | O15146 |
Chromosome Location : | 9q31.3-q32 |
Pathway : | ECM proteoglycans; Extracellular matrix organization |
Function : | ATP binding; protein binding; protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
MUSK-5457H | Recombinant Human Muscle, Skeletal, Receptor Tyrosine Kinase, GST-tagged | +Inquiry |
MUSK-2466H | Recombinant Human MUSK Protein, His-tagged | +Inquiry |
MUSK-2460H | Recombinant Human MUSK protein(31-490 aa), C-His-tagged | +Inquiry |
MUSK-1288M | Recombinant Mouse MUSK Protein, His-SUMO/MYC-tagged | +Inquiry |
MUSK-3547H | Recombinant Human MUSK Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionIn autoimmune myasthenia gravis, immunosuppressive therapies and acetylcholinesterase inhibitors are commonly used to manage symptoms, and some treatments specifically target the immune response against MUSK.
Yes, genetic testing and other diagnostic measures can identify MUSK protein abnormalities early in life, enabling prompt intervention and management.
Yes, diagnostic tests such as genetic testing and antibody assays can be employed to identify MUSK-related disorders.
MUSK protein plays a role in signaling pathways that contribute to muscle regeneration, making it an important factor in tissue repair.
Yes, gene therapy approaches aimed at restoring normal MUSK function are being explored as potential treatments for MUSK-related disorders.
Customer Reviews (3)
Write a reviewThe MUSK protein's high quality, stellar technical support, and compatibility with diverse experimental approaches make it an optimal choice for meeting my research needs.
Its usage in these techniques is highly praised by scientists worldwide, attesting to its effectiveness and significance in advancing scientific knowledge and understanding.
Its ability to consistently provide accurate and reliable results makes it an invaluable tool for quantifying and detecting specific targets in biological samples.
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