Recombinant Human ANTXR2, His-tagged

• Cat.No.: ANTXR2-269H
• Product Overview: ANTXR2, 34-317aa, Human, His tag, E.coli

Specification

• Description: ANTXR2 is called anthrax toxin receptor 2 because it allows the toxin that causes anthrax to attach to cells and trigger disease. This protein is involved in the formation of tiny blood vessels (capillaries). It is also important for maintaining the structure of basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Recombinant human ANTXR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 1mM DTT, 0.1M NaCl
• Molecular Mass: 33.0 kDa(307aa) confirmed by MALDI-TOF
• Protein length: 34-317aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSQEQPSCR RAFDLYFVLD KSGSVANNWI EIYNFVQQLA ERFVSPEMRL SFIVFSSQAT IILPLTGDRG KISKGLEDLK RVSPVGETYI HEGLKLANEQ IQKAGGLKTS SIIIALTDGK LDGLVPSYAE KEAKISRSLG ASVYCVGVLD FEQAQLERIA DSKEQVFPVK GGFQALKGII NSILAQSCTE ILELQPSSVC VGEEFQIVLS GRGFMLGSRN GSVLCTYTVN ETYTTSVKPV SVQLNSMLCP APILNKAGET LDVSVSFNGG KSVISGSLIV TATECSN
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ANTXR2 anthrax toxin receptor 2 [ Homo sapiens ]
• Official Symbol: ANTXR2
• Synonyms: ANTXR2; anthrax toxin receptor 2; capillary morphogenesis protein 2; CMG 2; CMG2; FLJ31074; capillary morphogenesis gene 2 protein; ISH; JHF; CMG-2; MGC45856; MGC111533
• Gene ID: 118429
• mRNA Refseq: NM_001145794
• Protein Refseq: NP_001139266
• MIM: 608041
• UniProt ID: P58335
• Chromosome Location: 4q21.3
• Pathway: Cellular roles of Anthrax toxin, organism-specific biosystem
• Function: metal ion binding; protein binding; receptor activity