"CHCHD3" Related Products

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Recombinant Human coiled-coil-helix-coiled-coil-helix domain containing 3, His-tagged

Cat.No.: CHCHD3-295H
Product Overview: CHCHD3, 1-227aa, Human, His tag, E.coli
Description: Coiled-coil-helix-coiled-coil-helix domain containing protein 3, also known as CHCHD3, is required for maintenance of mitochondrial crista integrity and mitochondrial function. This protein may act as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. It has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Recombinant human CHCHD3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Molecular Mass: 28.5 kDa (250aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGGTTST RRVTFEADEN ENITVVKGIR LSENVIDRMK ESSPSGSKSQ RYSGAYGASV SDEELKRRVA EELALEQAKK ESEDQKRLKQ AKELDRERAA ANEQLTRAIL RERICSEEER AKAKHLARQL EEKDRVLKKQ DAFYKEQLAR LEERSSEFYR VTTEQYQKAA EEVEAKFKRY ESHPVCADLQ AKILQCYREN THQTLKCSAL ATQYMHCVNH AKQSMLEKGG
Purity: >80% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25mg/ml (determined by Bradford assay)
Gene Name: CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 [ Homo sapiens ]
Official Symbol: CHCHD3
Synonyms: CHCHD3; coiled-coil-helix-coiled-coil-helix domain containing 3; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; FLJ20420; MINOS3; mitochondrial inner membrane organizing system 3; PPP1R22; protein phosphatase 1; regulatory subunit 22; protein phosphatase 1, regulatory subunit 22;
Gene ID: 54927
mRNA Refseq: NM_017812
Protein Refseq: NP_060282
MIM: 613748
UniProt ID: Q9NX63
Chromosome Location: 7q33
Function: phosphatase binding; protein binding; protein complex scaffold;

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