Recombinant Human calcium/calmodulin-dependent protein kinase II inhibitor 1, His-tagged

• Cat.No.: CAMK2N1-470H
• Product Overview: CAMK2N1, 1-78aa Human, His tag, E.coli

Specification

• Description: CAMK2N1 belongs to the CAMK2N family. This protein interacts with CAMK2B; the presence of Ca2+/calmodulin increases the interaction but is not essential. It also interacts with CAMK2A; this interaction requires CAMK2A activation by Ca2+. CAMK2N1 is potent and specific inhibitor of CaM-kinase II (CAMK2). Recombinant human CAMK2N1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
• Molecular Mass: 10.9kDa (101aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEVLPY GDEKLSPYGD GGDVGQIFSC RLQDTNNFFG AGQNKRPPKL GQIGRSKRVV IEDDRIDDVL KNMTDKAPPG V
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 [ Homo sapiens ]
• Official Symbol: CAMK2N1
• Synonyms: PRO1489; RP11-401M16.1; calcium/calmodulin-dependent protein kinase II inhibitor 1; CaMKIINalpha; CAMK2N1
• Gene ID: 55450
• mRNA Refseq: NM_018584.5
• Protein Refseq: NP_061054.2
• UniProt ID: Q7Z7J9
• Chromosome Location: 1p36.12
• Function: calcium-dependent protein kinase inhibitor activity; protein kinase binding