"HPR" Related Products

Recombinant Human haptoglobin-related protein, His-tagged

Cat.No.: HPR-484H
Product Overview: HPR, 20-348aa Human, His tag, E.coli
Description: HPR, also known as Haptoglobin-related protein, is a primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL) particles shown to be a part of the innate immune defense. HPR-bound hemoglobin might contribute to the biologic activity of the circulating apoL-I/Hpr-containing HDL particles. Recombinant human HPR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 1mM DTT,0.15M NaCl
Molecular Mass: 39.3 kDa(352aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSLYSGNDV TDISDDRFPK PPEIANGYVE HLFRYQCKNY YRLRTEGDGV YTLNDKKQWI NKAVGDKLPE CEAVCGKPKN PANPVQRILG GHLDAKGSFP WQAKMVSHHN LTTGATLINE QWLLTTAKNL FLNHSENATA KDIAPTLTLY VGKKQLVEIE KVVLHPNYHQ VDIGLIKLKQ KVLVNERVMP ICLPSKNYAE VGRVGYVSGW GQSDNFKLTD HLKYVMLPVA DQYDCITHYE GSTCPKWKAP KSPVGVQPIL NEHTFCVGMS KYQEDTCYGD AGSAFAVHDL EEDTWYAAGI LSFDKSCAVA EYGVYVKVTS IQHWVQKTIA EN
Purity: >85% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: HPR?haptoglobin-related protein [?Homo sapiens?(human) ]
Official Symbol: HPR
Synonyms: HPR; HP; A-259H10.2; haptoglobin-related protein; Haptoglobin-related locus
Gene ID: 3250
mRNA Refseq: NM_020995
Protein Refseq: NP_066275
MIM: 140210
UniProt ID: P00739
Chromosome Location: 16q22.1
Pathway: African trypanosomiasis; Binding and Uptake of Ligands by Scavenger Receptors; Scavenging of Heme from Plasma
Function: catalytic activity; hemoglobin binding

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