Recombinant Human cold shock domain containing C2, RNA binding, His-tagged

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Recombinant Human cold shock domain containing C2, RNA binding, His-tagged

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Cat.No. : CSDC2-549H
Product Overview : CSDC2, 1-153aa, Human His tag, E.coli
Description : CSDC2, as known as cold shock domain-containing protein C2, is RNA-binding factor which binds specifically to the very 3"-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. The cold shock domain containing proteins (CSDPs) are one group of the evolutionarily conserved nucleic acid-binding proteins widely distributed in bacteria, plants, animals, and involved in various cellular processes, including adaptation to low temperature, cellular growth, nutrient stress and stationary phase. It may play a central role in the negative regulation of histone variant synthesis in the developing brain. Recombinant human CSDC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Molecular Mass : 19.2 kDa(176aa) confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMTSESTS PPVVPPLHSP KSPVWPTFPF HREGSRVWER GGVPPRDLPS PLPTKRTRTY SATARASAGP VFKGVCKQFS RSQGHGFITP ENGSEDIFVH VSDIEGEYVP VEGDEVTYKM CPIPPKNQKF QAVEVVLTQL APHTPHETWS GQVVGS
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : CSDC2 cold shock domain containing C2, RNA binding [ Homo sapiens ]
Official Symbol : CSDC2
Synonyms : CSDC2; cold shock domain containing C2, RNA binding; cold shock domain-containing protein C2; PIPPin; RNA-binding protein pippin; PIPPIN; dJ347H13.2;
Gene ID : 27254
mRNA Refseq : NM_014460
Protein Refseq : NP_055275
UniProt ID : Q9Y534
Chromosome Location : 22q13.2
Function : DNA binding; RNA binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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