"CSDC2" Related Products

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Recombinant Human cold shock domain containing C2, RNA binding, His-tagged

Cat.No.: CSDC2-549H
Product Overview: CSDC2, 1-153aa, Human His tag, E.coli
Description: CSDC2, as known as cold shock domain-containing protein C2, is RNA-binding factor which binds specifically to the very 3"-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. The cold shock domain containing proteins (CSDPs) are one group of the evolutionarily conserved nucleic acid-binding proteins widely distributed in bacteria, plants, animals, and involved in various cellular processes, including adaptation to low temperature, cellular growth, nutrient stress and stationary phase. It may play a central role in the negative regulation of histone variant synthesis in the developing brain. Recombinant human CSDC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Molecular Mass: 19.2 kDa(176aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTSESTS PPVVPPLHSP KSPVWPTFPF HREGSRVWER GGVPPRDLPS PLPTKRTRTY SATARASAGP VFKGVCKQFS RSQGHGFITP ENGSEDIFVH VSDIEGEYVP VEGDEVTYKM CPIPPKNQKF QAVEVVLTQL APHTPHETWS GQVVGS
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: CSDC2 cold shock domain containing C2, RNA binding [ Homo sapiens ]
Official Symbol: CSDC2
Synonyms: CSDC2; cold shock domain containing C2, RNA binding; cold shock domain-containing protein C2; PIPPin; RNA-binding protein pippin; PIPPIN; dJ347H13.2;
Gene ID: 27254
mRNA Refseq: NM_014460
Protein Refseq: NP_055275
UniProt ID: Q9Y534
Chromosome Location: 22q13.2
Function: DNA binding; RNA binding;

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