"BRCA2" Related Products


Recombinant Human BRCA2, His & GST-tagged

Cat.No.: BRCA2-232H
Product Overview: A DNA sequence encoding the human BCCIP (AAH09771.1) (Met1-Val314) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Source: Baculovirus-Insect Cells
Species: Human
Tag: His & GST
Form: Lyophilized from sterile PBS, pH7.4.
Molecular Mass: The recombinant human BCCIP/GST chimera consists of 551 amino acids and has a calculated molecular mass of 64 kDa. The recombinant protein migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
Protein length: Met1-Val314
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: >85 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name: BRCA2 breast cancer 2, early onset [ Homo sapiens ]
Official Symbol: BRCA2
Synonyms: BRCA2; breast cancer 2, early onset; FACD, FANCD, FANCD1, Fanconi anemia, complementation group D1; breast cancer type 2 susceptibility protein; BRCA1/BRCA2 containing complex; subunit 2; BRCC2; FAD; FAD1; fanconi anemia group D1 protein; breast cancer 2 tumor suppressor; BRCA1/BRCA2-containing complex, subunit 2; breast cancer susceptibility protein BRCA2; breast and ovarian cancer susceptibility gene, early onset; FACD; GLM3; FANCB; FANCD; PNCA2; FANCD1; BROVCA2;
Gene ID: 675
mRNA Refseq: NM_000059
Protein Refseq: NP_000050
MIM: 600185
UniProt ID: P51587
Chromosome Location: 13q12-q13
Pathway: DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; FOXM1 transcription factor network, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem;
Function: DNA binding; H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; gamma-tubulin binding; NOT histone acetyltransferase activity; protease binding; protein binding; single-stranded DNA binding;

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