Recombinant Human BRCA2, His & GST-tagged BRCA2-232H

Recombinant Human BRCA2, His & GST-tagged

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Recombinant Human BRCA2, His & GST-tagged

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Cat.No. : BRCA2-232H
Product Overview : A DNA sequence encoding the human BCCIP (AAH09771.1) (Met1-Val314) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Source : Baculovirus-Insect Cells
Species : Human
Tag : His & GST
Form : Lyophilized from sterile PBS, pH7.4.
Molecular Mass : The recombinant human BCCIP/GST chimera consists of 551 amino acids and has a calculated molecular mass of 64 kDa. The recombinant protein migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
Protein length : Met1-Val314
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >85 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70℃
Storage : Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : BRCA2 breast cancer 2, early onset [ Homo sapiens ]
Official Symbol : BRCA2
Synonyms : BRCA2; breast cancer 2, early onset; FACD, FANCD, FANCD1, Fanconi anemia, complementation group D1; breast cancer type 2 susceptibility protein; BRCA1/BRCA2 containing complex; subunit 2; BRCC2; FAD; FAD1; fanconi anemia group D1 protein; breast cancer 2 tumor suppressor; BRCA1/BRCA2-containing complex, subunit 2; breast cancer susceptibility protein BRCA2; breast and ovarian cancer susceptibility gene, early onset; FACD; GLM3; FANCB; FANCD; PNCA2; FANCD1; BROVCA2;
Gene ID : 675
mRNA Refseq : NM_000059
Protein Refseq : NP_000050
MIM : 600185
UniProt ID : P51587
Chromosome Location : 13q12-q13
Pathway : DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; FOXM1 transcription factor network, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem;
Function : DNA binding; H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; gamma-tubulin binding; NOT histone acetyltransferase activity; protease binding; protein binding; single-stranded DNA binding;

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