| Description : |
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. |
| Source : |
Nicotiana benthamiana |
| Species : |
Human |
| Form : |
Lyophilized |
| Molecular Mass : |
45,122 Da |
| Protein length : |
407 |
| Purity : |
>97% by SDS-PAGE gel |
| Notes : |
Small volumes of Activin-B recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
| Storage : |
This lyophilized preparation is stable at 2-8 degree C for short term, long storage it should be kept at -20 degree C. Reconstituted protein should be stored in working aliquots at -20 degree C and it is recommended to add a carrier protein (0.1% HSA or BSA). Repeated freezing and thawing is not recommended. |
| Warning : |
This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
