Recombinant Human ASB14, His-tagged

• Cat.No.: ASB14-3473H
• Product Overview: Ankyrin repeat and SOCS box protein 14 (ASB14)

Specification

• Description: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 302
• Purity: >90%
• Notes: Small volumes of ASB14 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ASB14 ankyrin repeat and SOCS box containing 14 [ Homo sapiens ]
• Official Symbol: ASB14
• Synonyms: ankyrin repeat and SOCS box protein 14; ankyrin repeat and SOCS box-containing 14; ankyrin repeat domain-containing SOCS box protein Asb-14
• Gene ID: 142686
• mRNA Refseq: NM_001142733
• Protein Refseq: NP_001136205
• UniProt ID: A6NK59
• Chromosome Location: 3p21.1
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem

Reviews

07/29/2022

Researchers who have utilized the ASB14 protein laud its reliability and effectiveness in their studies.

05/01/2021

In addition to its exceptional quality, the ASB14 protein is backed by excellent technical support offered by the manufacturer.

12/09/2017

Its superior quality, combined with the manufacturer's exceptional technical support, provides researchers with the confidence they need to conduct successful experiments and obtain meaningful results.

Q&As

Is ASB14 associated with cancer development or progression?

The association of ASB14 with cancer is not extensively studied. More research is needed to investigate its potential involvement in cancer biology.

Is ASB14 associated with any diseases?

Limited information is available regarding the association of ASB14 with specific diseases. Further research is required to determine its potential roles or associations.

Can ASB14 regulate cell growth and proliferation?

ASB14 may have a role in regulating cell growth and proliferation by modulating the stability of certain proteins involved in these processes.

Could ASB14 impact synaptic plasticity?

Although the association of ASB14 with synaptic plasticity is not well-documented, its expression in neuronal cells suggests a potential role in modulating this process.

Is ASB14 involved in neural development?

The specific involvement of ASB14 in neural development is not extensively studied. Further research is necessary to determine if it plays a role in this process.

Where is ASB14 expressed?

ASB14 is primarily expressed in the brain, specifically in neuronal cells.

Can ASB14 influence protein-protein interactions?

ASB14 may have the ability to influence protein-protein interactions through its ankyrin repeat domain, but specific interaction partners are not well-defined.