Recombinant Human LPHN1 cell lysate
- Specification
- Gene Information
- Related Products
Description : |
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms |
Species : |
Human |
Size : |
100 ul |
Storage Buffer : |
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : |
Western Blot; |
Gene Name : |
LPHN1 latrophilin 1 [ Homo sapiens ] |
Official Symbol : |
LPHN1 |
Synonyms : |
LPHN1; latrophilin 1; latrophilin-1; CIRL1; KIAA0821; LEC2; CIRL-1; lectomedin-2; calcium-independent alpha-latrotoxin receptor 1; CL1; |
Gene ID : |
22859 |
mRNA Refseq : |
NM_001008701 |
Protein Refseq : |
NP_001008701 |
UniProt ID : |
O94910 |
Chromosome Location : |
19p13.2 |
Pathway : |
GPCRs, Class B Secretin-like, organism-specific biosystem; |
Function : |
G-protein coupled receptor activity; latrotoxin receptor activity; receptor activity; signal transducer activity; sugar binding; toxin binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.