"LPHN1" Related Products


Recombinant Human LPHN1 cell lysate

Cat.No.: LPHN1-1029HCL
Description: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: LPHN1 latrophilin 1 [ Homo sapiens ]
Official Symbol: LPHN1
Synonyms: LPHN1; latrophilin 1; latrophilin-1; CIRL1; KIAA0821; LEC2; CIRL-1; lectomedin-2; calcium-independent alpha-latrotoxin receptor 1; CL1;
Gene ID: 22859
mRNA Refseq: NM_001008701
Protein Refseq: NP_001008701
UniProt ID: O94910
Chromosome Location: 19p13.2
Pathway: GPCRs, Class B Secretin-like, organism-specific biosystem;
Function: G-protein coupled receptor activity; latrotoxin receptor activity; receptor activity; signal transducer activity; sugar binding; toxin binding;

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