Recombinant Human LPHN1 Protein

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Recombinant Human LPHN1 Protein

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Cat.No. : LPHN1-4720H
Product Overview : Human LPHN1 full-length ORF (AAH19928.1) recombinant protein without tag.
Description : This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms
Source : Wheat Germ
Species : Human
Form : Liquid
Molecular Mass : 20.8 kDa
AA Sequence : MGLISHLERL MAEGKWGGTG VVEGMGMAEE GAGNGKAVWG MGRGKGERSP SLSSTFPQGR RSQVPGLGSG HPCSGRLDPK SQTPEAPGSG CVLSTCPGPL LSSLSGQPPQ PPSLNSRGSI APGHPSPAPA LPFPQRWPLH LCSDLSPSLC PSFSHKCHEF SNIFGSQPAA AMNFVGLRGR GSRKELGGRG QVGGWRDPFC C
Applications : Antibody Production
Functional Study
Compound Screening
Usage : Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
Gene Name : LPHN1 latrophilin 1 [ Homo sapiens ]
Official Symbol : LPHN1
Synonyms : LPHN1; latrophilin 1; latrophilin-1; CIRL1; KIAA0821; LEC2; CIRL-1; lectomedin-2; calcium-independent alpha-latrotoxin receptor 1; CL1;
Gene ID : 22859
mRNA Refseq : NM_001008701
Protein Refseq : NP_001008701
UniProt ID : O94910

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