"MYO3A" Related Products


Recombinant Human MYO3A cell lysate

Cat.No.: MYO3A-1160HCL
Description: The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: MYO3A myosin IIIA [ Homo sapiens ]
Official Symbol: MYO3A
Synonyms: MYO3A; myosin IIIA; deafness, autosomal recessive 30 , DFNB30; myosin-IIIa; DFNB30;
Gene ID: 53904
mRNA Refseq: NM_017433
Protein Refseq: NP_059129
MIM: 606808
UniProt ID: Q8NEV4
Chromosome Location: 10p11.1
Function: ADP binding; ATP binding; actin binding; actin-dependent ATPase activity; calmodulin binding; microfilament motor activity; microfilament motor activity; nucleotide binding; plus-end directed microfilament motor activity; protein kinase activity; protein serine/threonine kinase activity;

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