Recombinant Human PELI3 cell lysate

• Cat.No.: PELI3-1331HCL

Specification

• Description: Toll-like receptors (TLRs; see MIM 603030) and IL1R (IL1R1; MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PELI3 pellino E3 ubiquitin protein ligase family member 3 [ Homo sapiens ]
• Official Symbol: PELI3
• Synonyms: PELI3; pellino E3 ubiquitin protein ligase family member 3; pellino homolog 3 (Drosophila); E3 ubiquitin-protein ligase pellino homolog 3; MGC35521; pellino homolog 3; protein pellino homolog 3
• Gene ID: 246330
• mRNA Refseq: NM_001243135
• Protein Refseq: NP_001230064
• MIM: 609827
• UniProt ID: Q8N2H9
• Chromosome Location: 11q13.2
• Pathway: Activated TLR4 signalling, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IRAK1 recruits IKK complex, organism-specific biosystem; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem
• Function: ligase activity