"PELI3" Related Products

Recombinant Human PELI3 cell lysate

Cat.No.: PELI3-1331HCL
Description: Toll-like receptors (TLRs; see MIM 603030) and IL1R (IL1R1; MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: PELI3 pellino E3 ubiquitin protein ligase family member 3 [ Homo sapiens ]
Official Symbol: PELI3
Synonyms: PELI3; pellino E3 ubiquitin protein ligase family member 3; pellino homolog 3 (Drosophila); E3 ubiquitin-protein ligase pellino homolog 3; MGC35521; pellino homolog 3; protein pellino homolog 3;
Gene ID: 246330
mRNA Refseq: NM_001243135
Protein Refseq: NP_001230064
MIM: 609827
UniProt ID: Q8N2H9
Chromosome Location: 11q13.2
Pathway: Activated TLR4 signalling, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IRAK1 recruits IKK complex, organism-specific biosystem; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem;
Function: ligase activity;

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