Recombinant Human PYGB cell lysate

• Cat.No.: PYGB-1449HCL

Specification

• Description: The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PYGB phosphorylase, glycogen; brain [ Homo sapiens ]
• Official Symbol: PYGB
• Synonyms: PYGB; phosphorylase, glycogen; brain; glycogen phosphorylase, brain form; glycogen phosphorylase B; GPBB; MGC9213
• Gene ID: 5834
• mRNA Refseq: NM_002862
• Protein Refseq: NP_002853
• MIM: 138550
• UniProt ID: P11216
• Chromosome Location: 20
• Pathway: Glucose metabolism, organism-specific biosystem; Glycogen Metabolism, organism-specific biosystem; Glycogen breakdown (glycogenolysis), organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem
• Function: drug binding; glycogen phosphorylase activity; protein homodimerization activity; pyridoxal phosphate binding; sugar binding; transferase activity, transferring glycosyl groups