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Recombinant Human PYGB cell lysate

Cat.No.: PYGB-1449HCL
Description: The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: PYGB phosphorylase, glycogen; brain [ Homo sapiens ]
Official Symbol: PYGB
Synonyms: PYGB; phosphorylase, glycogen; brain; glycogen phosphorylase, brain form; glycogen phosphorylase B; GPBB; MGC9213;
Gene ID: 5834
mRNA Refseq: NM_002862
Protein Refseq: NP_002853
MIM: 138550
UniProt ID: P11216
Chromosome Location: 20
Pathway: Glucose metabolism, organism-specific biosystem; Glycogen Metabolism, organism-specific biosystem; Glycogen breakdown (glycogenolysis), organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem;
Function: drug binding; glycogen phosphorylase activity; protein homodimerization activity; pyridoxal phosphate binding; sugar binding; transferase activity, transferring glycosyl groups;

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