||Recombinant Human Topo-IIβ encoding C-Terminal 300 amino acids expressed inE.coli. The Topo-IIβ is purified by proprietary chromatographic techniques.
||Topo-II Beta plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is present ubiquitously in normal cells and is upregulated in tumors and proliferating cells. Topo II Beta is also implicated in drug resistance of tumor cells.
||Sterile filtered liquid.
||Topo-II beta protein at 100 µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
||On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 59kDa.
||• ELISA • Inhibition Assays • Western Blotting.
||Store vial at -20ºC to -80ºC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.