Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human ABCA7

Cat.No. : ABCA7-753H
Product Overview : Recombinant Human ABCA7 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Human
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 [ Homo sapiens ]
Official Symbol : ABCA7
Gene ID : 10347
mRNA Refseq : NM_019112.3
Protein Refseq : NP_061985.2
MIM : 605414
UniProt ID : B3KUJ3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (9)

Ask a question
Are your recombinant protein products full-length proteins or protein domains? 04/14/2023

Our products have full-length proteins and protein parts, you can check the details in the product overview.

What biological processes are ABCA7 involved in? 04/14/2023

ABCA7 is involved in lipid transport, phagocytosis, visual learning, and positive regulation of cholesterol efflux.

Do you have biotinylated ABCA7 protein products? 04/14/2023

We do. Our products can be customized according to different needs of customers, and the labels that can be added include biotin, fluorescein, alexa flour, APC, etc.

How does abca7 contribute to AD-related pathology? 04/14/2023

ABCA7 loss of function significantly increases amyloid precursor protein proteolysis and amyloid-β production.

Which expression systems can be used to express the abca7 gene? 04/14/2023

Expression systems such as HEK293 and CHO can be used.

Can a GFP tag be added to study protein function? 04/14/2023

Some studies added green fluorescent protein to the C-terminus of ABCA7, which did not affect the lipid release reaction.

Is the ABCA7 variant a susceptibility locus for late-onset AD? 04/14/2023

Cumulative genetic evidence collected through genome-wide studies (GWAS) has identified ABCA7 variants as late-onset AD susceptibility loci, including rs3764650, rs3752246, and rs115550680.

How ABCA7 limits amyloid-beta production? 04/14/2023

ABCA7 limits amyloid-β production by regulating amyloid-β A4 precursor protein endocytosis and/or processing.

Does ABCA7 transport phosphatidylcholine? 04/14/2023

it does. But when phosphatidylcholine and phosphatidylserine are present at the same time, ABCA7 will preferentially transport phosphatidylserine.

Customer Reviews (2)

Write a review
Reviews
06/19/2021

    Rich catalog of recombinant protein products, no need to look for protein products everywhere.

    07/12/2020

      Customizable, very convenient

      Ask a Question for All ABCA7 Products

      Required fields are marked with *

      My Review for All ABCA7 Products

      Required fields are marked with *

      0

      Inquiry Basket

      cartIcon
      logo

      FOLLOW US

      Terms and Conditions        Privacy Policy

      Copyright © 2024 Creative BioMart. All Rights Reserved.

      Contact Us

      • /

      Stay Updated on the Latest Bioscience Trends