Recombinant Human SYN1, MYC/DDK-tagged SYN1-16H

Recombinant Human SYN1, MYC/DDK-tagged


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Recombinant Human SYN1, MYC/DDK-tagged

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Cat.No. : SYN1-16H
Product Overview : Recombinant Human SYN1, transcript variant Ia, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description : This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Source : HEK293 cells
Species : Human
Molecular Mass : 73.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : SYN1 synapsin I [ Homo sapiens (human) ]
Official Symbol : SYN1
Synonyms : SYN1; synapsin I; SYNI; SYN1a; SYN1b; synapsin-1; brain protein 4.1
Gene ID : 6853
mRNA Refseq : NM_006950
Protein Refseq : NP_008881
MIM : 313440
UniProt ID : P17600
Chromosome Location : Xp11.23
Pathway : BDNF signaling pathway; Monoamine Transport; Neurotransmitter Release Cycle
Function : ATP binding; calcium-dependent protein binding; catalytic activity

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