Recombinant Human RAPGEF3, MYC/DDK-tagged

• Cat.No.: RAPGEF3-135H
• Product Overview: Recombinant Human RAPGEF3, transcript variant 2, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Description: Rap guanine nucleotide exchange factor 3 is a protein that in humans is encoded by the RAPGEF3 gene.
• Source: HEK293 cells
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 99.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 [ Homo sapiens (human) ]
• Official Symbol: RAPGEF3
• Synonyms: RAPGEF3; Rap guanine nucleotide exchange factor (GEF) 3; EPAC; EPAC1; bcm910; HSU79275; MGC21410; CAMP-GEFI; Rap guanine nucleotide exchange factor 3; 9330170P05Rik; exchange protein directly activated by cAMP 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; cAMP-GEFI; cAMP-regulated guanine nucleotide exchange factor I; Epac 1
• Gene ID: 10411
• mRNA Refseq: NM_006105
• Protein Refseq: NP_006096
• MIM: 606057
• UniProt ID: O95398
• Chromosome Location: 12q13.1
• Pathway: Adaptive Immune System; Adrenergic signaling in cardiomyocytes; Integrated Pancreatic Cancer Pathway
• Function: Rap guanyl-nucleotide exchange factor activity; cAMP-dependent protein kinase regulator activity; guanyl-nucleotide exchange factor activity