Recombinant Human ARSB, His-tagged


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Recombinant Human ARSB, His-tagged

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Cat.No. : ARSB-1062H
Product Overview : Recombinant Human ARSB(Ser37-Met533), fused with a C-terminal 10-His tag, was expressed in CHO Cells.
Description : Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Source : CHO Cells
Species : Human
Tag : His
Predicted N Terminal : Ser37
Form : Supplied as a 0.2 µm filtered solution in Tris and NaCl.
Bio-activity : Measured by its ability to hydrolyze the substrate 4-Nitrocatechol Sulfate (PNCS). The specific activity is >3,000 pmol/min/µg.
Molecular Mass : Predicted Molecular Mass: 57 kDaSDS-PAGE: 80 kDa, reducing conditions
Endotoxin : < 1.0 EU per 1 μg of the protein by the LAL method.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles.6 months from date of receipt, -20 to -70 ºC as supplied.3 months, -20 to -70 ºC under sterile conditions after opening.
Gene Name : ARSB arylsulfatase B [ Homo sapiens (human) ]
Official Symbol : ARSB
Synonyms : ARSB; arylsulfatase B; ASB; G4S; MPS6; N-acetylgalactosamine-4-sulfatase; NP_000037.2; EC; NP_942002.1
Gene ID : 411
mRNA Refseq : NM_000046
Protein Refseq : NP_000037
MIM : 611542
UniProt ID : P15848
Chromosome Location : 5q14.1
Pathway : CS/DS degradation; Chondroitin sulfate degradation; Chondroitin sulfate/dermatan sulfate metabolism
Function : N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; metal ion binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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