"ARSB" Related Products

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Recombinant Human ARSB, His-tagged

Cat.No.: ARSB-1062H
Product Overview: Recombinant Human ARSB(Ser37-Met533), fused with a C-terminal 10-His tag, was expressed in CHO Cells.
Description: Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Source: CHO Cells
Species: Human
Tag: His
Predicted N Terminal: Ser37
Form: Supplied as a 0.2 µm filtered solution in Tris and NaCl.
Bio-activity: Measured by its ability to hydrolyze the substrate 4-Nitrocatechol Sulfate (PNCS). The specific activity is >3,000 pmol/min/µg.
Molecular Mass: Predicted Molecular Mass: 57 kDaSDS-PAGE: 80 kDa, reducing conditions
Endotoxin: < 1.0 EU per 1 μg of the protein by the LAL method.
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles.6 months from date of receipt, -20 to -70 ºC as supplied.3 months, -20 to -70 ºC under sterile conditions after opening.
Gene Name: ARSB arylsulfatase B [ Homo sapiens (human) ]
Official Symbol: ARSB
Synonyms: ARSB; arylsulfatase B; ASB; G4S; MPS6; N-acetylgalactosamine-4-sulfatase; NP_000037.2; EC 3.1.6.12; NP_942002.1
Gene ID: 411
mRNA Refseq: NM_000046
Protein Refseq: NP_000037
MIM: 611542
UniProt ID: P15848
Chromosome Location: 5q14.1
Pathway: CS/DS degradation; Chondroitin sulfate degradation; Chondroitin sulfate/dermatan sulfate metabolism
Function: N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; metal ion binding

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