Native Bordetella pertussis Perrtussis toxin
| Cat.No. : | PT-141B |
| Product Overview : | This product was highly purified (>90% pure) from Bordetella pertussis strain Tohama. Cytotoxicity of the PT was confirmed by morphological alteration of CHO cells after treatment with 0.1 ng/ml of PT. |
- Specification
- Gene Information
- Related Products
| Description : | Perrtussis toxin (PT) is a protein-based AB5-type exotoxin produced by Bordeterra pertussis. PT catalyzes the ADP-ribosylation of the α subunits of the heterotrimeric guanine nucleotide regulatory proteins Gi, Go, and Gt and prevents intracellular signal transduction involving the G proteins. PT consists of one moplecule of each S1 (26 kDa), S2 (22 kDa), S3 (22 kDa), S5 (12 kDa) and two molecule of S4 (12 kDa). |
| Source : | Bordetella pertussis |
| Species : | Bordetella pertussis |
| Form : | 83 μg/ml in 10% glycerol 10 mM phoshate buffer (pH 7.4), 137 mM NaCl |
| Applications : | 1. Studies on the signal transduction of the trimeric GTP binding proteins. 2. Therapeutic role in treating a number of diseases including hypertention, viral and autoimumune inhibitions. |
| Storage : | Store at -70℃ |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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