Active Recombinant Human BMP2&BMP7

• Cat.No.: BMP2&BMP7-709H
• Product Overview: Recombinant Human BMP2&BMP7 (Accession # NP_001191 (BMP-2) & NP_001710 (BMP-7)) was produced in E. coli-derived.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Predicted N Terminal: Ala284 & Ser293
• Form: Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
• Bio-activity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351.The ED50 for this effect is typically 10 - 40 ng/mL.
• Molecular Mass: Recombinant Human BMP2&BMP7 has a calculated MW of 12.9 kDa (BMP-2), 15.8 kDa (BMP-7).
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 10 µg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: BMP2 bone morphogenetic protein 2 [ Homo sapiens ]
• Official Symbol: BMP2
• Synonyms: BMP2; bone morphogenetic protein 2; BMP2A; BMP-2A; bone morphogenetic protein 2A; BDA2
• Gene ID: 650
• mRNA Refseq: NM_001200
• Protein Refseq: NP_001191
• MIM: 112261
• UniProt ID: P12643
• Chromosome Location: 20p12