Recombinant Human cathepsin L1

• Cat.No.: CTSL1-91H
• Product Overview: Recombinant Human Cathepsin L encoding a.a. 1-87 expressed inE.coli,38 kDa.

Specification

• Cat. No.: CTSL1-91H
• Description: Cathepsins B, C, H, L, S, V, X/Z/P and 1 are cysteine proteases of the papain family. Cathepsin C is also known as DPPI (dipeptidyl-peptidase I). Cathepsin A is a serine carboxypeptidase and Cathepsin D and E are aspartic proteases. As lysosomal proteases, cathepsins play an important role in protein degradation. Because of their redistribution or increased levels in human and animal tumors, cathepsins may have a role in invasion and metastasis. Cathepsins are synthesized as inactive proenzymes and processed to become mature and active enzymes. Endogenous protein inhibitors, such as cystatins and some serpins, inhibit active enzymes.
• Source: E.coli.
• Presentation: Recombinant Human Cathepsin L protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
• Applications: •ELISA •Inhibition Assays •Western Blotting
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 38 kDa.
• Storage: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: CTSL1cathepsin L1 [ Homo sapiens ]
• Synonyms: CTSL1; cathepsin L1; MEP; CATL; CTSL; FLJ31037; CTSL1; cathepsin L; EC 3.4.22.15; OTTHUMP00000021601; OTTHUMP00000021602; OTTHUMP00000063566; Major excreted protein
• Gene ID: 1514
• mRNA Refseq: NM_001912
• Protein Refseq: NP_001903
• MIM: 116880
• UniProt ID: P07711
• Chromosome Location: 9q21.33
• Pathway: Antigen processing and presentation; Lysosome; Diabetes pathways
• Function: aminopeptidase activity;cysteine-type endopeptidase activity;kininogen binding;peptidase activity;peptide binding