Recombinant Bovine S100 Calcium Binding Protein G, Ca2+

• Cat.No.: S100G-162B
• Product Overview: Recombinant human Calbindin D9K was cloned from bovine cDNA and expressed inE.coli. It bounds to one Ca and one Ln ion. Two calcium ions are bound in the Calbindin D9K version. The protein consists of Calbindin D9K, mutant P47M (residues 5-79, swissprot accession P02633). MW = 8.5 kDa.

Specification

• Cat. No.: S100G-162B
• Description: Protein S100-G is aproteinthat in humans is encoded by the S100Ggene. This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increaseCa2+absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles.
• Source: E. Coli.
• Purity: > 95% by SDS-PAGE. The protein was observed as a single band migrating at molecular weight <10 kDa.
• Supplied As: solution in water pH 6. The concentration is calculated from the absorbance at 280nm (e280 = 1280 M-1 cm-1).
• Characteristics: Under the above described conditions, to avoid precipitation or protein dimerization, the product can be concentrated to a maximum of 2mM.
• Storage: -20ºC. The protein is stable at 4ºC for months and at 25 ºC for at least several weeks. After initial defrost, aliquot product into individual tubes and refreeze at -20ºC. Avoid repeated freeze/defrost cycles.

Gene Information

• Gene Name: S100G S100 calcium binding protein G [ Bos taurus ]
• Synonyms: S100G; S100 Calcium Binding Protein G; S100G; CABP; CALB3; S100D
• Gene ID: 281658
• mRNA Refseq: NM_174257
• Protein Refseq: NP_776682
• UniProt ID: P02633