Recombinant Human Parathyroid Hormone-like Hormone
Cat.No. : | PTHLH-111H |
Product Overview : | Recombinant Human PTHrP produced inE.Coliis a 9.8 kDa protein consisting of 86 amino acid residues. |
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Cat. No. : | PTHLH-111H |
Description : | Human Parathyroid Hormone-like related Protein (PTHrP) -is a member of the Parathyroid hormone family that is expressed in the mammary gland. It is known as a potent inhibitor of chondrocyte maturation. PTHrP is expressed by periarticular perichondrial cells and exerts its biological activity on PP-R expressing cells. During endochondral bone development PTHrP plays a major role in suppressing the onset of hypertrophic differentiation. It is also responsible for most cases of humoral hypercalcemia of malignancy. |
Supplied : | The sterile filtered solution is lyophilized from 0.5x PBS, pH 7.1. |
Source : | E.Coli. |
Reconstitution : | The lyophilized powder should be reconstituted in sterile DI water to a max concentration of 0.1-1mg/ml. Allow to set at least 30 minutes at 4°C, tighten cap and rotate to reconstitute any material on sides of vial. If desired, you can centrifuge at 1000 rpm for 1 minute to concentrate volume in bottom of vial. This solution can be diluted into water or other buffered solutions or stored at 4°Cfor up to 1 week or at – 20°Cfor future use. |
Note : | If this material is not to be used for coating or labeling(or other applications requiring carrier free material), the addition of 0.1% BSA to dilution buffers or dilution in sterile culture media is recommended to enhance stability and minimize absorption to vial. |
Endotoxin : | less than 0.1ng per ug. |
Reactivity : | not determined |
Purity : | >98% by SDS-Page and HPLC analysis. |
Storage : | The lyophilized powder is stable at room temperature for a few weeks but it is best stored desiccated at -20°C. Reconstituted material should be stored in working aliquots at -20°C.Please avoid freeze-thaw cycles. |
Publication : |
Measurements of Osteoanabolic agents PTH (1-34) and PTHrP (1-36) in therapeutic studies and clinical diagnostics. (2017)
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Gene Name : | PTHLH parathyroid hormone-like hormone [ Homo sapiens ] |
Synonyms : | PTHLH; parathyroid hormone-like hormone; HHM; PLP; PTHR; PTHRP; MGC14611; osteostatin; PTH-related protein; parathyroid-like protein; parathyroid hormone-like protein; humoral hypercalcemia of malignancy; parathyroid hormone-related protein; parathyroid hormone-like related protein; PTH-rP; PTHrP; parathyroid hormone-like hormone |
Gene ID : | 5744 |
mRNA Refseq : | NM_002820 |
Protein Refseq : | NP_002811 |
MIM : | 168470 |
UniProt ID : | P12272 |
Chromosome Location : | 12p12.1-p11.2 |
Function : | calcium ion binding; hormone activity |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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