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Guanosine monophosphate reductase 2

Cat.No. : CBCRY17
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  • Gene Information
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Cat. No. : CBCRY17
Background : Guanosine monophosphate reductase (GMPR) Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation.
Protein Classification : Oxidoreductase
Structure Weight : 161477.73 Da
Polymer : 1
Molecule : GMP reductase 2
Chain Length : 366 amino acids
PDB ID : 2A7R
MMDB ID : 37032
Source : E.coli
Method : X-Ray Diffraction
Resolution : 3.0 Å
Ligand Chemical Component : guanosine-5’-monophosphate; sulfate ion
Reference : Li, J., Wei, Z., Zheng, M., Gu, X., Deng, Y., Qiu, R., Chen, F., Ji, C., Gong, W., Xie, Y., Mao, Y.(2006) Crystal Structure of Human Guanosine Monophosphate Reductase 2 (GMPR2) in Complex with GMPJ.Mol.Biol.355: 980-988
Gene Name : GMPR2
Synonyms : MGC15084; MGC830; GMP reductase 2; guanosine 5"-monophosphate oxidoreductase 2; guanosine monophosphate reductase isolog; EC 1.7.1.7
UniProt ID : Q9P2T1
Gene ID : 51292
Chromosome Location : 14q12
Function : GMP reductase activity; metal ion binding; oxidoreductase activity; potassium ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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