"CTF1" Related Products


Recombinant Human Cardiotrophin 1, GST-tagged

Cat. No.: CTF1-184H
Description: The CCAAT-box Binding Protein 1 (CTF1, also called NF-I or NF-1) is a proline-rich transcription activator. It selectively activates transcription of genes that contain GCCAAT consensus sequence in promoter region, including human Ha-Ras, alpha-globin, hsp70 and many other cellular and viral genes. Cloning and functional characterization of the protein revealed that CTF1 contains a N-terminal DNA binding domain and a C-terminal proline-rich activation domain. CTF1 was shown to interact with the general transcription factor IIB (TFIIB) and facilitate the recruitment of TFIIB to TBP-DNA complexes, with the forkhead thyroid transcription factor TTF2 to regulate hormonedependent transcription of thyroperoxidase gene, as well as other receptor proteins to synergize hormone receptor-responsive activation. The proline-rich activation domain of human CTF1 protein (amino acids 399-499) is isolated from an E. coli strain that carries the coding sequence of the fused protein under the control of a T7 promoter. GST-CTF1 has been used for protein-protein interaction assays.
Source: E. coli.
Usage: For in vitro use only.
Form: Liquid. Supplied in 20 mM Tris-HCl pH 8.0, 100 mM KCl, 0.2 mM EDTA, 1 mM DTT and 20% glycerol.
Activity: 100 ng are sufficient for a protein-protein interaction assay.
Purity: > 95% by SDS-PAGE.
Storage: Quality guaranteed for 12 months, Store at -80℃. Avoid freeze / thaw cycles.
Gene Name: CTF1 cardiotrophin 1 [ Homo sapiens ]
Synonyms: CTF1; cardiotrophin 1; CT1; CT-1; cardiophin 1; Cardiotrophin-1
Gene ID: 1489
mRNA Refseq: NM_001142544
Protein Refseq: NP_001136016
MIM: 600435
UniProt ID: Q16619
Chromosome Location: 16p11.2
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function: cytokine activity; leukemia inhibitory factor receptor binding

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.