"HMBS" Related Products


Porphobilinogen deaminase

Cat. No.: CBCRY24
Background: The protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein Classification: Transferase
Structure Weight: 80152.23 Da
Polymer: 1
Molecule: Porphobilinogen deaminase
Chain Length: 364 amino acids
MMDB ID: 67075
Source: E.coli
Method: X-Ray Diffraction
Resolution: 2.18Å
Ligand Chemical Component: DPM
Reference: Song, G., Li, Y., Cheng, C., Zhao, Y., Gao, A., Zhang, R., Joachimiak, A., Shaw, N., Liu, Z.J. (2009) Structural insight into acute intermittent porphyria. Faseb J. 23: 396-404
Gene Name: HMBS
Synonyms: PBG-D; PBGD; UPS; porphobilinogen deaminase; pre-uroporphyrinogen synthase; uroporphyrinogen I synthase; uroporphyrinogen I synthetase; EC; hydroxymethylbilane synthase
UniProt ID: P08397
Gene ID: 3145
Chromosome Location: 11q23.3
Function: hydroxymethylbilane synthase activity; transferase activity

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.