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Recombinant Human Phosphatidylethanolamine Binding Protein 1

Cat.No. : PEBP1-1400H
Product Overview : Recombinant human PEBP1 was expressed inE.coliand purified by using conventional chromatography techniques. MW =21 kDa (187aa).
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Cat. No. : PEBP1-1400H
Description : Phosphatidylethanolamine binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein (RKIP), is a member of the phosphatidylethanolamine-binding protein family and a serine protease inhibitor which inhibits thrombin, neuropsin. PEBP1 plays a pivotal modulatory role in several protein kinase signaling cascades. Protein kinase C (PKC) phosphorylates PEBP1, resulting in release of Raf-1 and activation of MEK and ERK. Expressed in many tissues, PEBP1 is implicated in the regulation of such physiological processes as membrane biosynthesis, spermatogenesis, neural development, and metastasis suppression.
Source : E.coli.
Amino Acid Sequence : MPVDLSKWSG PLSLQEVDEQ PQHPLHVTYA GAAVDELGKV LTPTQVKNRP TSISWDGLDS GKLYTLVLTD PDAPSRKDPK YREWHHFLVV NMKGNDISSG TVLSDYVGSG PPKGTGLHRY VWLVYEQDRP LKCDEPILSN RSGDHRGKFK VASFRKKYEL RAPVAGTCYQ AEWDDYVPKL YEQLSGK
Form : Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol.
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Endotoxin Level : < 1.0 EU per 1 μg of protein (determined by LAL method).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : PEBP1 phosphatidylethanolamine binding protein 1 [ Homo sapiens ]
Synonyms : PEBP1; phosphatidylethanolamine binding protein 1; PBP; HCNP; PEBP; RKIP; prostatic binding protein; Raf kinase inhibitory protein; hippocampal cholinergic neurostimulating peptide; HCNPpp; PEBP-1; Neuropolypeptide h3; Prostatic-binding protein; Raf kinase inhibitor protein; Phosphatidylethanolamine-binding protein 1
Gene ID : 5037
mRNA Refseq : NM_002567
Protein Refseq : NP_002558
MIM : 604591
UniProt ID : P30086
Chromosome Location : 12q24
Function : ATP binding; lipid binding; mitogen-activated protein kinase binding; nucleotide binding; peptidase inhibitor activity; phosphatidylethanolamine binding; receptor binding; serine-type endopeptidase inhibitor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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