"CAMKK2" Related Products


Recombinant Human CAMKK2, GST-tagged, Active

Cat. No.: CAMKK2-270H
Product Overview: Recombinant full-length human CAMKK2 was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 88 kDa.
Description: CAMKK2 (CAMKKβ) is a member of the CAMKK family. It is broadly distributed in tissues with highest levels in brain, thymus, spleen, and testis. CaMKK2 undergoes intramolecular autophosphorylation, is regulated by Ca2+/calmodulin and phosphorylates CaMKI and CaMKIV on Thr177 and Thr200, respectively. CaMKK2 activates both CaMKI and CaMKIV when coexpressed in Jurkat T cells. CaMKK2 also phosphorylates and regulates the activity of AMPK, which is an important regulator of cellular metabolism in response to metabolic stress.
Source: Sf9 insect cells using baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta [ Homo sapiens ]
Synonyms: CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2, beta; CAMKK; CAMKKB; KIAA0787; MGC15254; calcium/calmodulin-dependent protein kinase kinase 2 beta; CAMKK beta protein; calcium/calmodulin-dependent protein kinase beta; EC; CaM-KK beta; CaM-kinase kinase beta; CaMKK beta; Calcium/calmodulin-dependent protein kinase kinase beta
Gene ID: 10645
mRNA Refseq: NM_006549
Protein Refseq: NP_006540
UniProt ID: Q96RR4
Chromosome Location: 12q24.2
Pathway: Adipocytokine signaling pathway
Function: ATP binding; calcium ion binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding; protein tyrosine kinase activity; transferase activity

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