Recombinant Human Aurora Kinase C, GST-tagged, Active
Cat.No. : | AURKC-248H |
Product Overview : | Recombinant full-length human AURORAC was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 61 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | AURKC-248H |
Description : | Aurora C is a member of mitotic serine/threonine kinases that regulate centrosome maturation, chromosome segregation, and cytokinesis. Aurora C has been shown to contribute to oncogenic transformation and is frequently overexpressed and amplified in many human tumors. Aurora C overexpression has been correlated with centrosome amplification, which can be a driving cause of genomic instability in tumor cells. Aurora C is an important regulator of both genomic integrity and cell cycle progression in cancer cells and is an attractive target for anticancer drug development. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | AURKC aurora kinase C [ Homo sapiens ] |
Synonyms : | aurora kinase C; AIE2; AIK3; ARK3; AurC; STK13; aurora-C; AURKC; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 3; serine/threonine kinase 13 (aurora/IPL1-like); EC 2.7.11.1; Aurora-C; Aurora/Ipl1-related kinase 3; Aurora/Ipl1/Eg2 protein 2 |
Gene ID : | 6795 |
mRNA Refseq : | NM_001015878 |
Protein Refseq : | NP_001015878 |
MIM : | 603495 |
UniProt ID : | Q9UQB9 |
Chromosome Location : | 19q13.43 |
Function : | protein serine/threonine kinase activity; ATP binding; nucleotide binding; transferase activity |
Products Types
◆ Recombinant Protein | ||
Aurkc-532R | Recombinant Rat Aurkc Protein, His-tagged | +Inquiry |
AURKC-1114H | Recombinant Human AURKC Protein (S2-S309), Tag Free | +Inquiry |
AURKC-1115H | Recombinant Human AURKC Protein (S2-S309), GST tagged | +Inquiry |
Aurkc-531M | Recombinant Mouse Aurkc Protein, His-tagged | +Inquiry |
AURKC-530H | Recombinant Human AURKC Protein, His-tagged | +Inquiry |
◆ Lysates | ||
AURKC-8559HCL | Recombinant Human AURKC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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