Recombinant Human AMPK (A1/B1/G1), His-tagged, Active
| Cat.No. : | AMPK(A1/B1/G1)-241H |
| Product Overview : | Recombinant full-length human AMPK (combination of A1/B1/G1 subunits) was expressed by baculovirus inSf9 insect cellsusing a C-terminal His tags. MW = 68kDa (A1), 38kDa (B1), 40kDa (G1). |
- Specification
- Gene Information
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| Cat. No. : | AMPK (A1/B1/G1)-241H |
| Description : | AMPK is a heterotrimer protein kinase consisting of an α catalytic subunit, and non-catalytic β and γ subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol. |
| Source : | Sf9 insect cells using baculovirus. |
| Sequence : | Full-length. |
| Applications : | Kinase Assay, Western Blot. |
| Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Gene Name : | PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit [ Homo sapiens ],PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit [ Homo sapiens ],PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit [ Homo sapiens ] |
| Synonyms : | protein kinase, AMP-activated, alpha 1 catalytic subunit; AMPK; AMPKa1; MGC33776; MGC57364; PRKAA1; AMPK alpha 1; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha-1; 5"-AMP-activated protein kinase, catalytic alpha-1 chain; AMPK1EC; 2.7.11.1; AMPK alpha-1 chain, protein kinase, AMP-activated, beta 1 non-catalytic subunit; AMPK; HAMPKb; MGC17785; PRKAB1; AMPK beta 1; AMPK beta -1 chain; AMP-activated protein kinase beta subunit; 5"-AMP-activated protein kinase beta-1 subunit; protein kinase, AMP-activated, noncatalytic, beta-1; AMPKb; protein kinase, AMP-activated, beta 1 non-catalytic subunit, protein kinase, AMP-activated, gamma 1 non-catalytic subunit; AMPKG; MGC8666; PRKAG1; AMPK gamma-1 chain; 5"-AMP-activated protein kinase, gamma-1 subunit; AMPKg; protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| Gene ID : | 5562,5564,5571 |
| mRNA Refseq : | NM_006251,NM_006253,NM_002733 |
| Protein Refseq : | NP_006242,NP_006244,NP_002724 |
| MIM : | 602739,602740,602742 |
| UniProt ID : | Q13131, Q9Y478, P54619 |
| Chromosome Location : | 5p12, 12q24.1, 12q12-q14 |
| Pathway : | Adipocytokine signaling pathway; Hypertrophic cardiomyopathy (HCM); Insulin signaling pathway; Regulation of autophagy; mTOR signaling pathway, Adipocytokine signaling pathway; Hypertrophic cardiomyopathy (HCM); Insulin signaling pathway, Adipocytokine signaling pathway; Hypertrophic cardiomyopathy (HCM); Insulin signaling pathway |
| Function : | ATP binding; cAMP-dependent protein kinase activity; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity, protein binding; protein kinase binding, AMP binding; AMP-activated protein kinase activity; cAMP-dependent protein kinase activity; cAMP-dependent protein kinase regulator activity; protein binding; protein kinase binding |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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